MSM Cellular Detox

Try Human Improvement risk free! If you don't love it, we will issue you a full refund within 60 days of your first order for the cost of the product.

Due to shipping constraints, this is only valid for orders in the continental US. Maximum refund value is $70.

Everyone's body is different, but most people start to see a noticeable impact after 14 days of daily use and larger changes after 30 days. Consistency is key to seeing benefits since it takes some time for the MSM to build in your system!

The taste is fairly bitter but it washes it right away with water, juice, coffee, or whatever beverage you want. To make the cellular detox as pure and effective as possible, we did not use any additional flavoring or ingredients.

It takes a little bit of time to get used to it but lots of people end up craving it after taking for a few weeks!

Start with a low dose with ¼-½ tsp (¼-½ scoop) twice a day and work up to 1 tsp (1 scoop) twice a day or as directed by your healthcare provider.

To make the cellular detox as pure and effective as possible, we did not use any additional flavoring or ingredients. So the flavor is a bit bitter but it washes out right away. Here are the best ways to take it.

• Warm-water shot:

Dissolve your scoop in 1–2 oz of warm water, take it quickly, then follow with water, coffee, or juice. Channel your inner college self, we promise it is way easier than a tequila shot! This is the most popular way.

• Direct scoop:

Scoop the MSM directly into your mouth then swallow down with water or whatever beverage you want to use as a chaser, citrus works especially well. This is the Human Improvement team favorite way and we promise it isn’t as intimidating as it sounds!

• Coffee or juice mini-mix:

Swap the water for a small amount of coffee or juice. This is one of the easiest ways to mask the taste of the MSM.

• Lemon water:

Adding a squeeze of lemon to your water can brighten the flavor and the acidity helps mask the MSM taste.

And here is a quick video of our favorite ways.

There is a ton of misinformation out there on silicon dioxide which can make things confusing! Silicon dioxide is a natural compound found in many foods and even naturally inside the body.

There are two types, amorphous, which is what is generally found in food products and crystalline which is found in materials like quartz and sand.

Amorphous silicon dioxide, which is what we use, is well studied and classified as safe in foods. When ingested, amorphous silica is poorly absorbed by the gut and is typically excreted without significant metabolism or accumulation in the body. 

In fact, it is often used in significantly higher doses as a detox agent itself as it can help the body dispose of aluminum. It also supports the structural organization and stability of collagen, elastin, and connective tissue though we don't use nearly enough to see those benefits.

Crystalline silicon dioxide, on the other hand, is what can pose some health risks but that is when it is inhaled. Furthermore, that concern primarily applies to industrial or occupational exposure (e.g. grind mortar, saw, drill concrete, or manufacture brick, concrete, stone, or ceramic) by breathing in dust, not oral ingestion.

So when people start talking about the dangers of silicon dioxide, they are most often mixing up the two and talk about the health risks of inhaling crystalline silicon dioxide, not ingesting amorphous silicon dioxide.

Silicon dioxide makes up less than 0.5% of a serving in the MSM Cellar Detox and it makes it significantly smoother and helps it dissolve in water. Without that, it is very crystalline and is difficult to dissolve which a lot of customers complained about plus it tastes way worse!

Yes you can! MSM does not contain sulfonamides, so it is generally safe for those with sulfa allergies. MSM is an organic sulfur compound, but it is not a sulfonamide. There is no known cross-reactivity between sulfonamide drugs and MSM. That being said, it is always good to start with a low dose and work up from there!

Many people with MTHFR variants take MSM without issue. However, because of potential differences in sulfur metabolism and detoxification, we always suggest people with MTHFR variants start with smaller doses and work their way up!

MSM contains sulfur which is involved in detoxification pathways in the liver. Because of this, some people with MTHFR (or other genetic variations) who have impaired detoxification or sulfur-processing pathways may find sulfur-containing supplements beneficial—or, in some cases, they may be more sensitive to them.

While MSM does contain a “methyl” component in its name (methylsulfonylmethane), its primary function in the body is not tied to the same folate- and B-vitamin–dependent methylation pathways as 5-MTHF or methylcobalamin (methylated B12).

No you don't! MSM supports detoxification by enhancing cellular function and promoting the body’s natural elimination pathways—like liver, kidneys, and lymph—not by forcefully mobilizing large amounts of toxins like some aggressive detoxes. That said, if someone is doing a more intense or targeted detox protocol, adding a binder could be helpful. But for daily cellular support and detox, most people do well with MSM on its own.

While there’s no official cure for long COVID, MSM may help support your recovery—especially if you’re dealing with fatigue, brain fog, muscle aches, or inflammation.

MSM is known for its powerful anti-inflammatory and antioxidant effects. It helps reduce oxidative stress, supports your body’s natural detox pathways, and promotes a more balanced immune response—all of which can be disrupted in long COVID.

It’s not a magic bullet, but for many people, MSM can be a valuable part of feeling like themselves again.

You can learn more here.

The vast majority of people tolerate MSM extremely well—with no side effects at all. But because MSM supports your body’s natural detox pathways, a small subset of users may experience some mild, temporary discomfort when they first start taking it.

This can include things like slight fatigue, mild headaches, or digestive changes—all signs that your body is beginning to release and process stored toxins. These effects typically fade quickly as your system adjusts. Staying hydrated and consistent with your daily dose can help ease the transition.

You can take as long as it continues to make you feel good! Some people take it for a few months to clean out their cells and reduce systemic inflammation but most people continue to take it because it makes them feel so good!

MSM is generally well-tolerated and has a very low risk of interacting with prescription medications. It’s not known to interfere with most drug pathways, and there are no widely documented interactions with common medications.

That said, because everyone’s health and medication profile is unique, we always recommend checking with your healthcare provider before starting MSM — especially if you’re taking blood thinners, diabetes medications, or undergoing treatment for a specific condition.

When in doubt, it’s best to start with a lower dose and see how your body responds.

No you don’t but you certainly can! The most important thing is to take it consistently. The MSM has a short half life in your system and it takes time to build up so make sure to take it daily to see the best results.

Start with ½ tsp (½ scoop) twice a day and work up to 1 tsp (1 scoop) twice a day or as directed by your healthcare provider.

Put the MSM directly on your tongue and swallow with water or dissolve directly into 2oz of water. For the best experience, use hot water when dissolving. Many people also like to use coffee or juice since they have a stronger flavor to wash out the taste of the MSM.

You can check out our favorite ways to take it here.

MSM contains approximately 34% organic sulfur by weight, making it one of the most efficient ways to deliver this essential mineral to your cells.

Sulfur is the 3rd most abundant mineral in your body and involved in over 150 vital bodily functions. Unfortunately, due to current farming practices and our food systems, many people are currently deficient.

You can read all about organic sulfur and why it is important here.